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How Yeast Chromosomes Avoid the Bad Breaks
The human genome is peppered with repeated DNA elements that can vary from a few to thousands of consecutive copies of the same sequence. During meiosis—the cell division that produces sperm and eggs—repetitive elements place the genome at risk for...
Gonorrhea Acquires a Piece of Human DNA
If a human cell and a bacterial cell met at a speed-dating event, they would never be expected to exchange phone numbers, much less genetic material. In more scientific terms, a direct transfer of DNA has never been recorded from humans to bacteria. Until...
You are What Your Father Ate
Scientists at the University of Massachusetts Medical School and the University of Texas at Austin have uncovered evidence that environmental influences experienced by a father can be passed down to the next generation, “reprogramming” how...
People with Specific Kind of Lung Cancer Respond to New Targeted Treatment
A study in the New England Journal of Medicine shows more than half of patients with a specific kind of lung cancer are responding positively to a treatment that targets the gene that drives their cancer. Science Brief thanks to EurekAlert. Read more...
Blocking an Oncogene in Liver Cancer Could be Potential Therapy Option
Scientists have found that a synthetic molecule they designed can block activation of a gene in liver cancer cells, halting a process that allows some of those cancer cells to survive chemotherapy. Without the interference of this gene’s function,...
Scientists At UCLA Map All Mammalian Gene Interactions
In one of the first efforts of its kind, UCLA researchers have taken mammalian genome maps, including human maps, one step further by showing not just the order in which genes fall in the genome but which genes actually interact.
Ronin Recruits Protein ‘allies’ to Sustain Embryonic Stem Cell Growth
Ronin, crucial to the self-renewal of embryonic stem cells, and a co-regulator called Hcf-1, binds to a small strand of DNA called a hyperconserved enhancer element to control a gene “program” that stimulates growth of the stem cells and may...
Twin Study Shows Mediterranean-style Diet Improves Heart Function
Following a Mediterranean-style diet may reduce the risk of heart disease by maintaining heart rate variability.The more a participant’s eating pattern matched a Mediterranean-style diet, the greater his heart rate variability. Genes do not entirely...
