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Genetic Regulation of Metabolomic Biomarkers – Paths to Cardiovascular Diseases And Type 2 Diabetes
In a study to the genetic variance of human metabolism, researchers have identified thirty one regions of the genome that were associated with levels of circulating metabolites, i.e., small molecules that take part in various chemical reactions of human...
So Many Proteins, So Much Promise
The human genome has been mapped. Now, it’s on to proteins, a much more daunting task. There are 20,300 genes, but there are millions of distinct protein molecules in our bodies. Many of these hold keys to understanding disease and targeting treatment. A...
How Yeast Chromosomes Avoid the Bad Breaks
The human genome is peppered with repeated DNA elements that can vary from a few to thousands of consecutive copies of the same sequence. During meiosis—the cell division that produces sperm and eggs—repetitive elements place the genome at risk for...
Epigenetic ‘memory’ Key to Nature Versus Nurture
Researchers funded by the Biotechnology and Biological Sciences Research Council (BBSRC) at the John Innes Centre have made a discovery, reported July 24th in Nature, that explains how an organism can create a biological memory of some variable condition,...
Genetic Variant Linked to Development of Liver Cancer in Hepatitis C Virus Carriers
A genome-wide study by researchers at the RIKEN Center for Genomic Medicine, Hiroshima University Hospital and Sapporo-Kosei General Hospital has identified a genetic variant associated with the development of liver cancer in chronic hepatitis C virus...
Researchers Improve Method for Finding Genetic Mistakes That Fuel Cancer
A dramatically better computer tool for finding the genetic missteps that fuel cancer has been developed by St. Jude Children’s Research Hospital – Washington University Pediatric Cancer Genome Project investigators. Researchers are using the...
Deadly Bacteria May Mimic Human Proteins to Evolve Antibiotic Resistance
Deadly bacteria may be evolving antibiotic resistance by mimicking human proteins, according to a new study by the Translational Genomics Research Institute (TGen). This process of “molecular mimicry” may help explain why bacterial human pathogens,...
Bacterial Genome May Hold Answers to Mercury Mystery
A newly sequenced bacterial genome from a team led by the Department of Energy’s Oak Ridge National Laboratory could contain clues as to how microorganisms produce a highly toxic form of mercury. Methylmercury, a potent human neurotoxin, appears...
