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Cancer Sequencing Initiative Discovers Mutations Tied to Aggressive Childhood Brain Tumors
Researchers studying a rare, lethal childhood tumor of the brainstem discovered that nearly 80 percent of the tumors have mutations in genes not previously tied to cancer. Early evidence suggests the alterations play a unique role in other aggressive...
Immunological Mechanisms of Oncolytic Adenoviral Therapy
Cancer is one of the most common causes of death in humans. The conventional cancer therapies include surgery, radiotherapy, chemotherapy, and targeting therapies, which are intended to directly destroy and eliminate tumor cells. These treatments often...
New Queen’s University Research Sheds Light on Gene Destruction Linked to Aggressive Prostate Cancer
Researchers at Queen’s University in Kingston, Canada have identified a possible cause for the loss of a tumor suppressor gene (known as PTEN) that can lead to the development of more aggressive forms of prostate cancer. “This discovery gives...
Study Finds Brachytherapy Reduced Death Rates in High-risk Prostate Cancer Patients
Brachytherapy for high-risk prostate cancers patients has historically been considered a less effective modality, but a new study from radiation oncologists at the Kimmel Cancer Center at Jefferson suggests otherwise. A population-based analysis looking...
Many People Continue to Smoke After Being Diagnosed with Cancer
A new analysis has found that a substantial number of lung and colorectal cancer patients continue to smoke after being diagnosed. Published early online in CANCER, a peer-reviewed journal of the American Cancer Society, the study provides valuable information...
Abiraterone: Indication of Considerable Added Benefit in Certain Patients
Abiraterone (trade name: Zytiga®) has been approved since September 2011 for men with metastatic prostate cancer that is no longer responsive to hormone therapy and progresses further during or after therapy with the cytostatic drug docetaxel. In an...
Cleveland Clinic Researcher Discovers Genetic Cause of Thyroid Cancer
Cleveland Clinic researchers have discovered three genes that increase the risk of thyroid cancer, which is has the largest incidence increase in cancers among both men and women. Research led by Charis Eng, M.D., Ph.D., Chair and founding Director of...
Fish Oil May Hold Key to Leukemia Cure
A compound produced from fish oil that appears to target leukemia stem cells could lead to a cure for the disease, according to Penn State researchers. The compound — delta-12-protaglandin J3, or D12-PGJ3 — targeted and killed the stem cells...
